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Diseases
Disease

Cackle Fever

Cheaply made potions and elixirs are sometimes tainted by Cackle Fever, which affects Humanoids only (gnomes are...

XDMG · 2024
Disease

Sewer Plague

Fouled potions and alchemical waste can give rise to Sewer Plague, which incubates in sewers and refuse heaps and is...

XDMG · 2024
Disease

Sight Rot

Any Beast or Humanoid that drinks water tainted by Sight Rot must succeed on a DC 15 Constitution saving throw or...

XDMG · 2024
Disease

Blinding Sickness

Pain grips the creature's mind, and its eyes turn milky white. The creature has disadvantage on Wisdom checks and...

PHB · 2014
Disease

Cackle Fever

This disease targets humanoids, although gnomes are strangely immune. While in the grips of this disease, victims...

DMG · 2014
Disease

Filth Fever

A raging fever sweeps through the creature's body. The creature has disadvantage on Strength checks, Strength saving...

PHB · 2014
Disease

Flesh Rot

The creature's flesh decays. The creature has disadvantage on Charisma checks and vulnerability to all damage. This...

PHB · 2014
Disease

Mindfire

The creature's mind becomes feverish. The creature has disadvantage on Intelligence checks and Intelligence saving...

PHB · 2014
Disease

Seizure

The creature is overcome with shaking. The creature has disadvantage on Dexterity checks, Dexterity saving throws,...

PHB · 2014
Disease

Sewer Plague

Sewer plague is a generic term for a broad category of illnesses that incubate in sewers, refuse heaps, and stagnant...

DMG · 2014
Disease

Sight Rot

This painful infection causes bleeding from the eyes and eventually blinds the victim. A beast or humanoid that...

DMG · 2014
Disease

Slimy Doom

The creature begins to bleed uncontrollably. The creature has disadvantage on Constitution checks and Constitution...

PHB · 2014
Disease

Arcane Blight

Outside table sources

Any humanoid that spends 12 hours in the necropolis must succeed on a DC 15 Constitution saving throw or contract an...

IDRotF · 2014
Disease

Blue Mist Fever

Outside table sources

A magical mist creeps through the jungles of Chult. Contact with this thin, blue, odorless mist can infect giants...

ToA · 2014
Disease

Bluerot

Outside table sources

This disease targets humanoids. While afflicted with bluerot, a victim grows grotesque blue boils on their face and...

GoS · 2014
Disease

Frigid Woe

Outside table sources

Frigid woe is a special disease developed by Aeor's mages that cannot be cured by conventional treatment or magic....

EGW · 2014
Disease

Ghoul Gut

Outside table sources

Water polluted with ghoul parts carries ghoul gut. A creature drinking this tainted water must succeed on a DC 12...

OoW · 2014
Disease

Grackle-Lung

Outside table sources

The constant smog in Gracklstugh causes grackle-lung in living, breathing creatures, resulting in persistent,...

OotA · 2014
Disease

Lichen Plague

Outside table sources

A Beast, Giant, Humanoid, or Monstrosity that comes into contact with bile lichen spores is at risk of contracting a...

FRAiF · 2014
Disease

Mudpox

Outside table sources

Contact with dead oozes from the Underdark mixed with snowmelt and mud has been making people sick. Any Beast or...

FRAiF · 2014
Disease

Redface

Outside table sources

The effects of redface are identical to those of sight rot (see "Diseases" in chapter 8 of the Dungeon Master's...

GoS · 2014
Disease

Saprophytic Plague

Outside table sources

Xanthoria's research into lichdom and her creation of a living phylactery led to the emergence of the plague...

CM · 2014
Disease

Shaking Plague

Outside table sources

Magical experiments gone awry gave rise to Shaking Plague, which affects Humanoids. A creature suffers the following...

FRAiF · 2014
Disease

Shivering Sickness

Outside table sources

Insects native to the jungles and marshes of Chult carry this disease, shivering sickness. The easiest protection...

ToA · 2014
Disease

Spider Eggs

Outside table sources

If the party is defeated, stabilized characters awaken after 1d4 hours to find themselves cocooned in sticky webs...

WDMM · 2014
Disease

Super-Tetanus

Outside table sources

A creature that contracts the disease of super-tetanus is wracked with pain as its heart races and its muscles spasm...

TftYP · 2014
Disease

The Gnawing Plague

Outside table sources

The Gnawing Plague, also known as "the Gnaws," is known in every corner of Richemulot. Transmission The Gnaws is...

VRGR · 2014
Disease

The Rusting

Outside table sources

The Rusting manifests as a thin, iron coating that grows over a victim's body. When exposed to moisture, this iron...

FRAiF · 2014
Disease

Throat Leeches

Outside table sources

Minuscule parasites known as throat leeches infect the water in Chult's forests, swamps, and rivers. Any giant or...

ToA · 2014

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